{"id":777,"date":"2022-01-21T23:04:00","date_gmt":"2022-01-21T14:04:00","guid":{"rendered":"https:\/\/obgyn.jp\/?p=777"},"modified":"2024-03-04T00:03:14","modified_gmt":"2024-03-03T15:03:14","slug":"gc-bev","status":"publish","type":"post","link":"https:\/\/obgyn.jp\/?p=777","title":{"rendered":"GC\uff08GEM + CBDCA\uff09+ Bev \u7642\u6cd5\u30ec\u30b8\u30e1\u30f3"},"content":{"rendered":"\n

\u25c6\u5a66\u4eba\u79d1\u3067\u306e\u4fdd\u967a\u9069\u7528<\/h3>\n\n\n\n

\u304c\u3093\u85ac\u7269\u7642\u6cd5\u5f8c\u306b\u5897\u60aa\u3057\u305f\u5375\u5de3\u764c<\/h4>\n\n\n\n

\u25c6Emetic risk\uff1amoderate<\/a> <\/h3>\n\n\n\n

\u25c6\u6e1b\u91cf\u57fa\u6e96<\/h3>\n\n\n\n

Day 8\u5b9f\u65bd\u4e88\u5b9a\u65e5\u306e\u8840\u6db2\u691c\u67fb\u7d50\u679c\u306a\u3069\u306b\u3088\u3063\u3066\u306f\u3001GEM\u309250%\u6e1b\u91cf\u307e\u305f\u306f\u7701\u7565\u3002<\/p>\n\n\n\n

\u526f\u4f5c\u7528\u306e\u767a\u73fe\u72b6\u6cc1\u306b\u3088\u3063\u3066\u3001GEM\u3092800 mg\/m2\u306b\u6e1b\u91cf\u3059\u308b\uff08\u7b2c1\u6bb5\u968e\uff09\u3002\u3055\u3089\u306b\u3001\u526f\u4f5c\u7528\u306e\u767a\u73fe\u72b6\u6cc1\u306b\u3088\u3063\u3066Day-8\u3092\u7701\u7565\u3059\u308b\uff08\u7b2c2\u6bb5\u968e\uff09\u3002<\/p>\n\n\n\n

\u25c6\u6295\u4e0e\u5468\u671f\u3068\u56de\u6570<\/h3>\n\n\n\n

21\u65e5\u6bce\u30016-10 cycle\u3002\u305d\u306e\u5f8c\u306bBev\u7dad\u6301\u7642\u6cd5\u3092\u884c\u3046\u5834\u5408\u3001Bev\u5358\u5264\u3067PD\uff08Progressive Disease\uff09\u3068\u306a\u308b\u307e\u3067\u6295\u4e0e\u3057\u7d9a\u3051\u308b\u3002<\/p>\n\n\n\n

\u25c6\u6295\u4e0e\u9806\u3068\u6295\u4e0e\u91cf<\/h3>\n\n\n\n
Rp<\/strong><\/td>\u6297\u304c\u3093\u5264<\/strong><\/td>\u6295\u4e0e\u91cf<\/strong><\/td>\u6295\u4e0e\u6642\u9593<\/strong><\/td>\u6295\u4e0e\u65e5<\/strong><\/td><\/tr>
1<\/td>CBDCA<\/td>AUC = 4<\/td>1 h<\/td>Day 1<\/td><\/tr>
2<\/td>GEM<\/td>1000 mg\/m2<\/td>30 min<\/td>Day 1\u3001Day 8<\/td><\/tr>
3<\/td>\uff08Bev\uff09<\/td>15 mg\/kg<\/td>90-30 min<\/td>Day 1<\/td><\/tr><\/tbody><\/table><\/figure>\n\n\n
\u62d9\u8457\u300e\u5a66\u4eba\u79d1\u304c\u3093\u306e\u5206\u5b50\u75c5\u7406\u5b66\u3068\u6cbb\u7642\u30ec\u30b8\u30e1\u30f3\u300f<\/a>\u3082\u3054\u53c2\u7167\u304f\u3060\u3055\u3044\u3002<\/h5>\n\n
\u5375\u5de3\u304c\u3093\u306b\u4f7f\u3046\u85ac\u7269\u7642\u6cd5\u30ec\u30b8\u30e1\u30f3<\/h5>\r\n